Selective depletion of basophils ameliorates immunoglobulin E-mediated anaphylaxis

Selective depletion of basophils ameliorates immunoglobulin E-mediated anaphylaxis

Basophils, which are the rarest granulocytes, play crucial roles in protective immunity against parasites and development of allergic disorders. Although immunoglobulin (Ig)E-dependent responses via receptor for IgE (FcεRI) in basophils have been extensively studied, little is known about cell surfa...

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Bibliographic Details
Main Authors: Takeshi Nakamura, Tomohiro Fukaya, Tomofumi Uto, Hideaki Takagi, Keiichi Arimura, Tetsuya Tono, Katsuaki Sato
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Basophils
IgE
Type I hyperreactivity
Passive anaphylaxis
Intervention
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580816302849

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http://www.sciencedirect.com/science/article/pii/S2405580816302849

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