Cerenkov luminescence imaging is an effective preclinical tool for assessing colorectal cancer PD-L1 levels in vivo

Cerenkov luminescence imaging is an effective preclinical tool for assessing colorectal cancer PD-L1 levels in vivo

Abstract Background Preclinical and clinical studies have demonstrated that immunotherapy has effectively delayed tumor progression, and the clinical outcomes of anti-PD-1/PD-L1 therapy were related to PD-L1 expression level in the tumors. A 131I-labeled anti-PD-L1 monoclonal antibody tracer, 131I-P...

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Bibliographic Details
Main Authors: Sheng Zhao, Wenbin Pan, Huijie Jiang, Rongjun Zhang, Hao Jiang, Zonghui Liang, Hongbo Hu
Format: Article
Language:English
Published: SpringerOpen 2020-06-01
Series:EJNMMI Research
Subjects:
Colorectal cancer
Immunotherapy
Cerenkov luminescence imaging
Programmed death ligand-1
Preclinical tool
Online Access:http://link.springer.com/article/10.1186/s13550-020-00654-w

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http://link.springer.com/article/10.1186/s13550-020-00654-w

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