Computational Modeling of In Vitro Swelling of Mitochondria: A Biophysical Approach

Computational Modeling of In Vitro Swelling of Mitochondria: A Biophysical Approach

Swelling of mitochondria plays an important role in the pathogenesis of human diseases by stimulating mitochondria-mediated cell death through apoptosis, necrosis, and autophagy. Changes in the permeability of the inner mitochondrial membrane (IMM) of ions and other substances induce an increase in...

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Bibliographic Details
Main Authors: Vladimir I. Makarov, Igor Khmelinskii, Sabzali Javadov
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Molecules
Subjects:
mitochondria
biophysical modeling
mitochondrial swelling
permeability transition pore
kinetic analysis
matrix volume
calcium
Online Access:http://www.mdpi.com/1420-3049/23/4/783

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http://www.mdpi.com/1420-3049/23/4/783

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