Neutrophil-specific knockout demonstrates a role for mitochondria in regulating neutrophil motility in zebrafish
Neutrophils are fast-moving cells essential for host immune functions. Although they primarily rely on glycolysis for ATP, isolated primary human neutrophils depend on mitochondrial membrane potential for chemotaxis. However, it is not known whether mitochondria regulate neutrophil motility in vivo,...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2018-03-01
|
Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/11/3/dmm033027 |