Neutrophil-specific knockout demonstrates a role for mitochondria in regulating neutrophil motility in zebrafish
Neutrophils are fast-moving cells essential for host immune functions. Although they primarily rely on glycolysis for ATP, isolated primary human neutrophils depend on mitochondrial membrane potential for chemotaxis. However, it is not known whether mitochondria regulate neutrophil motility in vivo,...
Main Authors: | Wenqing Zhou, Lingyan Cao, Jacob Jeffries, Xiaoguang Zhu, Christopher J. Staiger, Qing Deng |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2018-03-01
|
Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/11/3/dmm033027 |
Similar Items
-
Determining macrophage versus neutrophil contributions to innate immunity using larval zebrafish
by: Emily E. Rosowski
Published: (2020-01-01) -
Pioneer neutrophils release chromatin within in vivo swarms
by: Hannah M Isles, et al.
Published: (2021-07-01) -
Protective Effect of Phillyrin on Lethal LPS-Induced Neutrophil Inflammation in Zebrafish
by: Liling Yang, et al.
Published: (2017-10-01) -
Nuclear Progestin Receptor (Pgr) Knockouts in Zebrafish Demonstrate Role for Pgr in Ovulation But Not in Rapid Nongenomic Steroid Mediated Meiosis Resumption
by: Yong eZhu, et al.
Published: (2015-03-01) -
Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library
by: Xingang Wang, et al.
Published: (2014-01-01)