A Co-Delivery System of Curcumin and p53 for Enhancing the Sensitivity of Drug-Resistant Ovarian Cancer Cells to Cisplatin

A Co-Delivery System of Curcumin and p53 for Enhancing the Sensitivity of Drug-Resistant Ovarian Cancer Cells to Cisplatin

In order to enhance the sensitivity of drug-resistant ovarian cancer cells to cisplatin (DDP), a co-delivery system was designed for simultaneous delivery of curcumin (CUR) and p53 DNA. Firstly, the bifunctional peptide K14 composed of tumor targeting peptide (tLyP-1) and nuclear localization signal...

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Bibliographic Details
Main Authors: Xinli Guo, Zhou Fang, Min Zhang, Deyu Yang, Shuyue Wang, Kehai Liu
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
ovarian cancer
drug resistance
polyethyleneimine
curcumin
p53
co-delivery system
Online Access:https://www.mdpi.com/1420-3049/25/11/2621

Internet

https://www.mdpi.com/1420-3049/25/11/2621

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