Physiologically Based Simulations of Deuterated Glucose for Quantifying Cell Turnover in Humans

In vivo [6,6-2H2]-glucose labeling is a state-of-the-art technique for quantifying cell proliferation and cell disappearance in humans. However, there are discrepancies between estimates of T cell proliferation reported in short (1-day) versus long (7-day) 2H2-glucose studies and very-long (9-week)...

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Bibliographic Details
Main Authors: Christoph Niederalt, Julio Lahoz-Beneytez, Stephan Schaller, Derek Macallan, Thomas Eissing, Becca Asquith
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Immunology
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Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00474/full