Viral Infection at High Magnification: 3D Electron Microscopy Methods to Analyze the Architecture of Infected Cells

Viral Infection at High Magnification: 3D Electron Microscopy Methods to Analyze the Architecture of Infected Cells

As obligate intracellular parasites, viruses need to hijack their cellular hosts and reprogram their machineries in order to replicate their genomes and produce new virions. For the direct visualization of the different steps of a viral life cycle (attachment, entry, replication, assembly and egress...

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Bibliographic Details
Main Authors: Inés Romero-Brey, Ralf Bartenschlager
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Viruses
Subjects:
transmission electron microscopy
electron tomography
serial sectioning
scanning transmission electron microscopy
serial block face-scanning electron microscopy
focus ion beam-scanning electron microscopy
virus-host interactions
cell membranes
ultrastructure
cryo-EM
Online Access:http://www.mdpi.com/1999-4915/7/12/2940

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http://www.mdpi.com/1999-4915/7/12/2940

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