Transcriptional effects of Organochlorine o,p′-DDT and its Metabolite p,p′-DDE in Transfected MDA-MB 231 and MCF-7 Breast Cancer Cell Lines

Transcriptional effects of Organochlorine o,p′-DDT and its Metabolite p,p′-DDE in Transfected MDA-MB 231 and MCF-7 Breast Cancer Cell Lines

Background: The organochlorine DDT has estrogenic activity but the mechanism underlying the estrogenic activity of this pesticide remains unclear. In the present investigation here, we studied the transcriptional effects of a synthetic organochlorine pesticide o,p’-DDT [1.1.1.-trichloro-2-(o-chlorop...

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Bibliographic Details
Main Authors: Ehsan zayerzadeh, Mohammad Kazem Koohi, Azadeh Fardipour
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences and Health Services 2015-04-01
Series:Research in Molecular Medicine
Subjects:
Organochlorinated pesticides
o
p’-DDT
MCF-7 cell line
thymidine kinase-ERE promoter.
Online Access:http://rmm.mazums.ac.ir/browse.php?a_code=A-10-683-4&slc_lang=en&sid=1

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http://rmm.mazums.ac.ir/browse.php?a_code=A-10-683-4&slc_lang=en&sid=1

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