Phenotypic mutation rates and the abundance of abnormal proteins in yeast.
Phenotypic mutations are errors that occur during protein synthesis. These errors lead to amino acid substitutions that give rise to abnormal proteins. Experiments suggest that such errors are quite common. We present a model to study the effect of phenotypic mutation rates on the amount of abnormal...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-11-01
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| Series: | PLoS Computational Biology |
| Online Access: | http://europepmc.org/articles/PMC2082502?pdf=render |