Origins and characterization of variants shared between databases of somatic and germline human mutations

Origins and characterization of variants shared between databases of somatic and germline human mutations

Abstract Background Mutations arise in the human genome in two major settings: the germline and the soma. These settings involve different inheritance patterns, time scales, chromatin structures, and environmental exposures, all of which impact the resulting distribution of substitutions. Nonetheles...

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Bibliographic Details
Main Authors: William Meyerson, John Leisman, Fabio C. P. Navarro, Mark Gerstein
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Bioinformatics
Subjects:
SNVs
Somatic genomics
Germline genomics
Genomic privacy
Categorical data analysis
Online Access:http://link.springer.com/article/10.1186/s12859-020-3508-8

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http://link.springer.com/article/10.1186/s12859-020-3508-8

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