Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes

Plasmodium falciparum causes the most severe form of malaria in humans and is responsible for over 700,000 deaths annually. It is an obligate intracellular parasite and invades erythrocytes where it grows in a relatively protected niche. Invasion of erythrocytes is essential for parasite survival an...

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Bibliographic Details
Main Authors: Lin Chen, Yibin Xu, Julie Healer, Jenny K Thompson, Brian J Smith, Michael C Lawrence, Alan F Cowman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/04187