In vivo imaging of injured cortical axons reveals a rapid onset form of Wallerian degeneration

In vivo imaging of injured cortical axons reveals a rapid onset form of Wallerian degeneration

Abstract Background Despite the widespread occurrence of axon and synaptic loss in the injured and diseased nervous system, the cellular and molecular mechanisms of these key degenerative processes remain incompletely understood. Wallerian degeneration (WD) is a tightly regulated form of axon loss a...

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Bibliographic Details
Main Authors: Alison Jane Canty, Johanna Sara Jackson, Lieven Huang, Antonio Trabalza, Cher Bass, Graham Little, Maria Tortora, Shabana Khan, Vincenzo De Paola
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Biology
Subjects:
Wallerian degeneration
Brain
Cortex
Cortical axons
In vivo imaging
Synapses
Online Access:http://link.springer.com/article/10.1186/s12915-020-00869-2

Internet

http://link.springer.com/article/10.1186/s12915-020-00869-2

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