Single dose of multi-clade virus-like particle vaccine protects chickens against clade 2.3.2.1 and clade 2.3.4.4 highly pathogenic avian influenza viruses

Single dose of multi-clade virus-like particle vaccine protects chickens against clade 2.3.2.1 and clade 2.3.4.4 highly pathogenic avian influenza viruses

Abstract Virus-like particles (VLPs) are recognized as an alternative vaccine platform that provide effective protection against various highly pathogenic avian influenza viruses (HPAIVs). Here, we developed multi-clade VLPs expressing two HAs (a chimera of clade 2.3.2.1c and clade 2.3.4.4c HA) with...

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Bibliographic Details
Main Authors: Yong-Myung Kang, Hyun-Kyu Cho, Ju Hun Kim, Su Jin Lee, Seo-Jeong Park, Do-Young Kim, Seong Yup Kim, Jung-won Park, Myoung-Heon Lee, Min-Chul Kim, Hyun-Mi Kang
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93060-8

Internet

https://doi.org/10.1038/s41598-021-93060-8

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