Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity.

The immune system comprises a complex network of specialized cells that protects against infection, eliminates cancerous cells, and regulates tissue repair, thus serving a critical role in homeostasis, health span, and life span. The subterranean-dwelling naked mole-rat (NM-R; Heterocephalus glaber)...

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Bibliographic Details
Main Authors: Hugo G Hilton, Nimrod D Rubinstein, Peter Janki, Andrea T Ireland, Nicholas Bernstein, Nicole L Fong, Kevin M Wright, Megan Smith, David Finkle, Baby Martin-McNulty, Margaret Roy, Denise M Imai, Vladimir Jojic, Rochelle Buffenstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000528