Determination of variability due to biological and technical variation in urinary extracellular vesicles as a crucial step in biomarker discovery studies

Determination of variability due to biological and technical variation in urinary extracellular vesicles as a crucial step in biomarker discovery studies

Urinary extracellular vesicles (EVs) are an attractive source of biomarkers for urological diseases. A crucial step in biomarker discovery studies is the determination of the variation parameters to perform a sample size calculation. In this way, a biomarker discovery study with sufficient statistic...

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Bibliographic Details
Main Authors: Eline Oeyen, Hanny Willems, Ruben ’T Kindt, Koen Sandra, Kurt Boonen, Lucien Hoekx, Stefan De Wachter, Filip Ameye, Inge Mertens
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
urine
variation
size exclusion chromatography
proteomics
lipidomics
lc-ms/ms
power analysis
sample size calculation
biomarker discovery
Online Access:http://dx.doi.org/10.1080/20013078.2019.1676035

Internet

http://dx.doi.org/10.1080/20013078.2019.1676035

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