A Coil-to-Helix Transition Serves as a Binding Motif for hSNF5 and BAF155 Interaction

A Coil-to-Helix Transition Serves as a Binding Motif for hSNF5 and BAF155 Interaction

Human SNF5 and BAF155 constitute the core subunit of multi-protein SWI/SNF chromatin-remodeling complexes that are required for ATP-dependent nucleosome mobility and transcriptional control. Human SNF5 (hSNF5) utilizes its repeat 1 (RPT1) domain to associate with the SWIRM domain of BAF155. Here, we...

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Bibliographic Details
Main Authors: Jeongmin Han, Iktae Kim, Jae-Hyun Park, Ji-Hye Yun, Keehyoung Joo, Taehee Kim, Gye-Young Park, Kyoung-Seok Ryu, Yoon-Joo Ko, Kenji Mizutani, Sam-Young Park, Rho Hyun Seong, Jooyoung Lee, Jeong-Yong Suh, Weontae Lee
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
BAF155
hSNF5
coupled folding and binding
NMR spectroscopy
X-ray crystallography
Online Access:https://www.mdpi.com/1422-0067/21/7/2452

Internet

https://www.mdpi.com/1422-0067/21/7/2452

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