Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.

Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.

Annual influenza epidemics and occasional pandemics pose a severe threat to human health. Host cell factors required for viral spread but not for cellular survival are attractive targets for novel approaches to antiviral intervention. The cleavage activation of the influenza virus hemagglutinin (HA)...

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Bibliographic Details
Main Authors: Bastian Hatesuer, Stephanie Bertram, Nora Mehnert, Mahmoud M Bahgat, Peter S Nelson, Stefan Pöhlmann, Klaus Schughart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24348248/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24348248/?tool=EBI

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