Novel Polyclonal Antibody Raised against Tetrodotoxin Using Its Haptenic Antigen Prepared from 4,9-anhydrotetrodotoxin Reacted with 1,2-Ethaneditiol and Further Reacted with Keyhole Limpet Hemocyanin

A novel polyclonal antibody against tetrodotoxin (TTX) was raised using its haptenic antigen, where 4,9-anhydroTTX was reacted with 1,2-ethanedithiol and this derivative was further reacted with keyhole limpet hemocyanin (KLH). This newly designed antigen (KLH-TTX) was inoculated into rabbits, resul...

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Bibliographic Details
Main Authors: Shigeru Sato, Suzuka Takaishi, Ko Yasumoto, Shugo Watabe
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/11/10/551