CEACAM1 regulates the IL-6 mediated fever response to LPS through the RP105 receptor in murine monocytes

CEACAM1 regulates the IL-6 mediated fever response to LPS through the RP105 receptor in murine monocytes

Abstract Background Systemic inflammation and the fever response to pathogens are coordinately regulated by IL-6 and IL-1β. We previously showed that CEACAM1 regulates the LPS driven expression of IL-1β in murine neutrophils through its ITIM receptor. Results We now show that the prompt secretion of...

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Bibliographic Details
Main Authors: Zhifang Zhang, Deirdre La Placa, Tung Nguyen, Maciej Kujawski, Keith Le, Lin Li, John E. Shively
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Immunology
Subjects:
CEACAM1
IL-6
Fever
LPS
Monocytes
RP105
Online Access:http://link.springer.com/article/10.1186/s12865-019-0287-y

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http://link.springer.com/article/10.1186/s12865-019-0287-y

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