Gold Nanoparticle-Based Fluorescent Theranostics for Real-Time Image-Guided Assessment of DNA Damage and Repair

Gold Nanoparticle-Based Fluorescent Theranostics for Real-Time Image-Guided Assessment of DNA Damage and Repair

Chemotherapeutic dosing, is largely based on the tolerance levels of toxicity today. Molecular imaging strategies can be leveraged to quantify DNA cytotoxicity and thereby serve as a theranostic tool to improve the efficacy of treatments. Methoxyamine-modified cyanine-7 (Cy7MX) is a molecular probe...

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Bibliographic Details
Main Authors: Shriya S. Srinivasan, Rajesh Seenivasan, Allison Condie, Stanton L. Gerson, Yanming Wang, Clemens Burda
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
Cy7MX-loaded gold nanoparticles
AP-targeted delivery
DNA repair mechanism
chemotheranostic
real-time imaging
molecular probe
Online Access:https://www.mdpi.com/1422-0067/20/3/471

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https://www.mdpi.com/1422-0067/20/3/471

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