Regulatory T Cells Suppress Effector T Cell Proliferation by Limiting Division Destiny

Understanding how the strength of an effector T cell response is regulated is a fundamental problem in immunology with implications for immunity to pathogens, autoimmunity, and immunotherapy. The initial magnitude of the T cell response is determined by the sum of independent signals from antigen, c...

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Bibliographic Details
Main Authors: Mark R. Dowling, Andrey Kan, Susanne Heinzel, Julia M. Marchingo, Philip D. Hodgkin, Edwin D. Hawkins
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02461/full