Levosimendan protects human hepatocytes from ischemia-reperfusion injury.

Levosimendan protects human hepatocytes from ischemia-reperfusion injury.

Ischemia-reperfusion injury (IRI) is a major challenge in liver transplantation. The mitochondrial pathway plays a pivotal role in hepatic IRI. Levosimendan, a calcium channel sensitizer, was shown to attenuate apoptosis after IRI in animal livers. The aim of this study was to investigate the effect...

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Bibliographic Details
Main Authors: Stefanie N Brunner, Nicolai V Bogert, Andreas A Schnitzbauer, Eva Juengel, Anton Moritz, Isabella Werner, Angela Kornberger, Andres Beiras-Fernandez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5690693?pdf=render

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http://europepmc.org/articles/PMC5690693?pdf=render

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