Mechanisms and direction of allocation bias in randomised clinical trials

Mechanisms and direction of allocation bias in randomised clinical trials

Abstract Background Selective allocation of patients into the compared groups of a randomised trial may cause allocation bias, but the mechanisms behind the bias and its directionality are incompletely understood. We therefore analysed the mechanisms and directionality of allocation bias in randomis...

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Bibliographic Details
Main Authors: Asger Paludan-Müller, David Ruben Teindl Laursen, Asbjørn Hróbjartsson
Format: Article
Language:English
Published: BMC 2016-10-01
Series:BMC Medical Research Methodology
Subjects:
Allocation bias
Selection bias
Bias mechanisms
Systematic review
Randomised clinical trials
Direction of bias
Online Access:http://link.springer.com/article/10.1186/s12874-016-0235-y

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http://link.springer.com/article/10.1186/s12874-016-0235-y

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