Immunomodulatory Effects of Domoic Acid Differ Between In vivo and In vitro Exposure in Mice

The immunotoxic potential of domoic acid (DA), a well-characterized neurotoxin, has not been fully investigated. Phagocytosis and lymphocyte proliferation were evaluated following in vitro and in vivo exposure to assay direct vs indirect effects. Mice were injected intraperitoneally with a single do...

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Bibliographic Details
Main Authors: Milton Levin, Heather Leibrecht, James Ryan, Frances Van Dolah, Sylvain De Guise
Format: Article
Language:English
Published: MDPI AG 2008-12-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/6/4/636/