Inhibition of Autophagy Prolongs Recipient Survival Through Promoting CD8+ T Cell Apoptosis in a Rat Liver Transplantation Model

Inhibition of Autophagy Prolongs Recipient Survival Through Promoting CD8+ T Cell Apoptosis in a Rat Liver Transplantation Model

In liver transplantation (LT), although various immunosuppressants have been used in clinical practice, acute rejection remains a common complication that significantly shortens recipient survival. In recent years, manipulating immune tolerance has been regarded as one of the promising solutions to...

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Bibliographic Details
Main Authors: Xiaolong Chen, Li Wang, Yinan Deng, Xuejiao Li, Guolin Li, Jing Zhou, Daorou Cheng, Yang Yang, Qing Yang, Guihua Chen, Genshu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
T cell
liver transplantation
acute rejection
autophagy
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01356/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01356/full

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