Double blind randomized controlled trial of deep brain stimulation for obsessive-compulsive disorder: Clinical trial design

Obsessive-compulsive disorder (OCD), a leading cause of disability, affects ~1–2% of the population, and can be distressing and disabling. About 1/3 of individuals demonstrate poor responsiveness to conventional treatments. A small proportion of these individuals may be deep brain stimulation (DBS)...

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Bibliographic Details
Main Authors: Nicole C.R. McLaughlin, Darin D. Dougherty, Emad Eskandar, Herbert Ward, Kelly D. Foote, Donald A. Malone, Andre Machado, William Wong, Mark Sedrak, Wayne Goodman, Brian H. Kopell, Fuad Issa, Donald C. Shields, Osama A. Abulseoud, Kendall Lee, Mark A. Frye, Alik S. Widge, Thilo Deckersbach, Michael S. Okun, Dawn Bowers, Russell M. Bauer, Dana Mason, Cynthia S. Kubu, Ivan Bernstein, Kyle Lapidus, David L. Rosenthal, Robert L. Jenkins, Cynthia Read, Paul F. Malloy, Stephen Salloway, David R. Strong, Richard N. Jones, Steven A. Rasmussen, Benjamin D. Greenberg
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Contemporary Clinical Trials Communications
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865421000867