c-Abl-TWIST1 Epigenetically Dysregulate Inflammatory Responses during Mycobacterial Infection by Co-Regulating Bone Morphogenesis Protein and miR27a

c-Abl-TWIST1 Epigenetically Dysregulate Inflammatory Responses during Mycobacterial Infection by Co-Regulating Bone Morphogenesis Protein and miR27a

Mycobacteria propelled modulation of host responses is of considerable interest in the face of emerging drug resistance. Although it is known that Abl tyrosine kinases affect entry and persistence of mycobacteria, mechanisms that couple c-Abl to proximal signaling pathways during immunity are poorly...

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Bibliographic Details
Main Authors: Kasturi Mahadik, Praveen Prakhar, R. S. Rajmani, Amit Singh, Kithiganahalli Narayanaswamy Balaji
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
mycobacteria
c-Abl
bone morphogenesis protein signaling
miRNA
TLR3
WhiB3
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00085/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00085/full

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