Differential expression of PTEN and PDCD4 tumor suppressors in melanoma and microRNA-21-positive melanoma cells and squamous carcinoma cells

Differential expression of PTEN and PDCD4 tumor suppressors in melanoma and microRNA-21-positive melanoma cells and squamous carcinoma cells

Background:In vitro cell experiments show that microRNA-21 downregulates the PTEN and PDCD4 tumor suppressor and promote melanoma cell proliferation and invasion. We examined microRNA-21, PTEN, and PDCD4 expressions in various melanoma cells as well as in melanoma specimens to define the actual expr...

Full description

Bibliographic Details
Main Authors: Kao-Hui Liu, Woan-Ruoh Lee, Ya-Ju Hsieh, Chia-Lun Chou, Ming-Chung Jiang, Shing-Chuan Shen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Dermatologica Sinica
Subjects:
Melanoma
microRNA-21
PDCD4
PTEN
Online Access:http://www.dermsinica.org/article.asp?issn=1027-8117;year=2019;volume=37;issue=1;spage=19;epage=27;aulast=Liu

Internet

http://www.dermsinica.org/article.asp?issn=1027-8117;year=2019;volume=37;issue=1;spage=19;epage=27;aulast=Liu

Similar Items