Synergy between CD8 T cells and Th1 or Th2 polarised CD4 T cells for adoptive immunotherapy of brain tumours.

The feasibility of cancer immunotherapy mediated by T lymphocytes is now a clinical reality. Indeed, many tumour associated antigens have been identified for cytotoxic CD8 T cells, which are believed to be key mediators of tumour rejection. However, for aggressive malignancies in specialised anatomi...

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Bibliographic Details
Main Authors: Sabine Hoepner, Jacelyn M S Loh, Cristina Riccadonna, Madiha Derouazi, Céline Yacoub Maroun, Pierre-Yves Dietrich, Paul R Walker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3662716?pdf=render