The big bang of genome editing technology: development and application of the CRISPR/Cas9 system in disease animal models

Targeted genome editing technology has been widely used in biomedical studies. The CRISPR-associated RNA-guided endonuclease Cas9 has become a versatile genome editing tool. The CRISPR/Cas9 system is useful for studying gene function through efficient knock-out, knock-in or chromatin modification of...

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Bibliographic Details
Main Authors: Ming SHAO, Tian-Rui XU, Ce-Shi CHEN
Format: Article
Language:English
Published: Science Press, PR China 2016-07-01
Series:Zoological Research
Subjects:
Online Access:http://www.zoores.ac.cn/EN/abstract/abstract3703.shtml