Performance of LBSap vaccine after intradermal challenge with L. infantum and saliva of Lu. longipalpis: immunogenicity and parasitological evaluation.

In the last decade, the search for new vaccines against canine visceral leishmaniasis has intensified. However, the pattern related to immune protection during long periods after experimental infection in vaccine trials is still not fully understood. Herein, we investigated the immunogenicity and pa...

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Main Authors: Bruno Mendes Roatt, Rodrigo Dian de Oliveira Aguiar-Soares, Juliana Vitoriano-Souza, Wendel Coura-Vital, Samuel Leôncio Braga, Rodrigo Corrêa-Oliveira, Olindo Assis Martins-Filho, Andréa Teixeira-Carvalho, Marta de Lana, Nelder Figueiredo Gontijo, Marcos José Marques, Rodolfo Cordeiro Giunchetti, Alexandre Barbosa Reis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3506642?pdf=render