On the relations of phase separation and Hi-C maps to epigenetics
The relationship between compartmentalization of the genome and epigenetics is long and hoary. In 1928, Heitz defined heterochromatin as the largest differentiated chromatin compartment in eukaryotic nuclei. Müller's discovery of position-effect variegation in 1930 went on to show that heteroch...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2020-03-01
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Series: | Royal Society Open Science |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.191976 |