On the relations of phase separation and Hi-C maps to epigenetics

The relationship between compartmentalization of the genome and epigenetics is long and hoary. In 1928, Heitz defined heterochromatin as the largest differentiated chromatin compartment in eukaryotic nuclei. Müller's discovery of position-effect variegation in 1930 went on to show that heteroch...

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Bibliographic Details
Main Authors: Prim B. Singh, Andrew G. Newman
Format: Article
Language:English
Published: The Royal Society 2020-03-01
Series:Royal Society Open Science
Subjects:
hp1
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.191976