Applying limiting entropy to quantify the alignment of collagen fibers by polarized light imaging

Collagen alignment has shown clinical significance in a variety of diseases. For instance, vulvar lichen sclerosus (VLS) is characterized by homogenization of collagen fibers with increasing risk of malignant transformation. To date, a variety of imaging techniques have been developed to visualize c...

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Bibliographic Details
Main Authors: Yingjie Qu, Zachary J. Smith, Kelly Tyler, Shufang Chang, Shuwei Shen, Mingzhai Sun, Ronald X. Xu
Format: Article
Language:English
Published: AIMS Press 2021-04-01
Series:Mathematical Biosciences and Engineering
Subjects:
vls
Online Access:http://www.aimspress.com/article/doi/10.3934/mbe.2021118?viewType=HTML