Novel Zinc Finger Transcription Factor ZFP580 Facilitates All-Trans Retinoic Acid -Induced Vascular Smooth Muscle Cells Differentiation by Rarα-Mediated PI3K/Akt and ERK Signaling

Novel Zinc Finger Transcription Factor ZFP580 Facilitates All-Trans Retinoic Acid -Induced Vascular Smooth Muscle Cells Differentiation by Rarα-Mediated PI3K/Akt and ERK Signaling

Background/Aims: Phenotypic switching of vascular smooth muscle cells (VSMC) plays a vital role in the development of vascular diseases. All-trans retinoic acid (ATRA) is known to regulate VSMC phenotypes. However, the underlying mechanisms remain completely unknown. Here, we have investigated the p...

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Bibliographic Details
Main Authors: Shuping Wei, Jingjing Zhang, Biao Han, Jianxun Liu, Xiaohui Xiang, Mei  Zhang, Shihai Xia, Wencheng Zhang, Xizheng Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Zfp580
Vascular smooth muscle cells
Differentiation
All-trans retinoic acid
Online Access:https://www.karger.com/Article/FullText/495098

Internet

https://www.karger.com/Article/FullText/495098

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