Hepatic overexpression of microsomal triglyceride transfer protein (MTP) results in increased in vivo secretion of VLDL triglycerides and apolipoprotein B

Hepatic overexpression of microsomal triglyceride transfer protein (MTP) results in increased in vivo secretion of VLDL triglycerides and apolipoprotein B

The microsomal triglyceride transfer protein (MTP) is essential for the hepatic secretion of apolipoprotein (apo) B-containing lipoproteins. Previous studies have indicated that inhibition of MTP results in decreased apoB plasma levels and decreased hepatic triglyceride secretion. However, the metab...

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Bibliographic Details
Main Authors: Uwe J.F. Tietge, Ahmed Bakillah, Cyrille Maugeais, Kazuhisa Tsukamoto, Mahmood Hussain, Daniel J. Rader
Format: Article
Language:English
Published: Elsevier 1999-11-01
Series:Journal of Lipid Research
Subjects:
recombinant adenovirus expressing MTP
apoB
triglyceride
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520324378

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http://www.sciencedirect.com/science/article/pii/S0022227520324378

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