Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data

Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data

Genetic polymorphisms in cytochrome P450 genes can cause alteration in metabolic activity of clinically important medicines. Thus, single nucleotide variants (SNVs) and copy number variations (CNVs) in CYP genes are leading factors of drug pharmacokinetics and toxicity and form pharmacogenetics biom...

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Bibliographic Details
Main Authors: Navid Neyshaburinezhad, Hengameh Ghasim, Mohammadreza Rouini, Youssef Daali, Yalda H. Ardakani
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Personalized Medicine
Subjects:
CYP450 enzymes
genetic polymorphism
personalized medicine
metabolism
Iranian population
Online Access:https://www.mdpi.com/2075-4426/11/8/804

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https://www.mdpi.com/2075-4426/11/8/804

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