Pseudomonas Quinolone Signal molecule PQS behaves like a B Class inhibitor at the IQ site of mitochondrial complex I

Pseudomonas Quinolone Signal molecule PQS behaves like a B Class inhibitor at the IQ site of mitochondrial complex I

Abstract Pseudomonas aeruginosa is a Gram‐negative bacterium of the proteobacteria class, and one of the most common causes of nosocomial infections. For example, it causes chronic pneumonia in cystic fibrosis patients. Patient sputum contains 2‐heptyl‐4‐hydroxyquinoline N‐oxide [HQNO] and Pseudomon...

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Bibliographic Details
Main Authors: Bettina Rieger, Sven Thierbach, Miriam Ommer, Finja S.V. Dienhart, Susanne Fetzner, Karin B. Busch
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:FASEB BioAdvances
Subjects:
HyPer‐3
IQ site inhibition
mitochondria
Pseudomonas aeruginosa
Pseudomonas quinolone signal (PQS)
Respiratory complex I
Online Access:https://doi.org/10.1096/fba.2019-00084

Internet

https://doi.org/10.1096/fba.2019-00084

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