Environmental Enrichment Improves Cognitive Deficits, AD Hallmarks and Epigenetic Alterations Presented in 5xFAD Mouse Model

Environmental Enrichment Improves Cognitive Deficits, AD Hallmarks and Epigenetic Alterations Presented in 5xFAD Mouse Model

Cumulative evidence shows that modifications in lifestyle factors constitute an effective strategy to modulate molecular events related to neurodegenerative diseases, confirming the relevant role of epigenetics. Accordingly, Environmental Enrichment (EE) represents an approach to ameliorate cognitiv...

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Bibliographic Details
Main Authors: Christian Griñán-Ferré, Vanesa Izquierdo, Eduard Otero, Dolors Puigoriol-Illamola, Rubén Corpas, Coral Sanfeliu, Daniel Ortuño-Sahagún, Mercè Pallàs
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
behavior
cognition
environmental enrichment
epigenetics
APP
Tau
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00224/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00224/full

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