Pentagone internalises glypicans to fine-tune multiple signalling pathways

Tight regulation of signalling activity is crucial for proper tissue patterning and growth. Here we investigate the function of Pentagone (Pent), a secreted protein that acts in a regulatory feedback during establishment and maintenance of BMP/Dpp morphogen signalling during Drosophila wing developm...

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Bibliographic Details
Main Authors: Mark Norman, Robin Vuilleumier, Alexander Springhorn, Jennifer Gawlik, George Pyrowolakis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/13301