Supersaturated polymeric micelles for oral silybin delivery: the role of the Soluplus–PVPVA complex

Increasing the degree of supersaturation of drugs and maintaining their proper stability are very important in improving the oral bioavailability of poorly soluble drugs by a supersaturated drug delivery system (SDDS). In this study, we reported a complex system of Soluplus–Copovidone (Soluplus–PVPV...

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Bibliographic Details
Main Authors: Chunliu Zhu, Shuang Gong, Jinsong Ding, Miaorong Yu, Ejaj Ahmad, Yi Feng, Yong Gan
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383518302533