Genetic Determinants Associated With in Vivo Survival of Burkholderia cenocepacia in the Caenorhabditis elegans Model

Genetic Determinants Associated With in Vivo Survival of Burkholderia cenocepacia in the Caenorhabditis elegans Model

A Burkholderia cenocepacia infection usually leads to reduced survival and fatal cepacia syndrome in cystic fibrosis patients. The identification of B. cenocepacia essential genes for in vivo survival is key to designing new anti-infectives therapies. We used the Transposon-Directed Insertion Sequen...

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Bibliographic Details
Main Authors: Yee-Chin Wong, Moataz Abd El Ghany, Raeece N. M. Ghazzali, Soon-Joo Yap, Chee-Choong Hoh, Arnab Pain, Sheila Nathan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Microbiology
Subjects:
Burkholderia cenocepacia
Caenorhabditis elegans
essential genes
TraDIS
in vivo survival
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01118/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01118/full

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