Antineuroinflammatory Activities and Neurotoxicological Assessment of Curcumin Loaded Solid Lipid Nanoparticles on LPS-Stimulated BV-2 Microglia Cell Models

Antineuroinflammatory Activities and Neurotoxicological Assessment of Curcumin Loaded Solid Lipid Nanoparticles on LPS-Stimulated BV-2 Microglia Cell Models

Curcumin, which is a potential antineuroinflammatory and neuroprotective compound, exhibits poor bioavailability in brain cells due to its difficulty in crossing the blood–brain barrier and its rapid metabolism during circulation, which decreases its efficacy in treating chronic neuroinflammatory di...

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Bibliographic Details
Main Authors: Palanivel Ganesan, Byungwook Kim, Prakash Ramalingam, Govindarajan Karthivashan, Vishnu Revuri, Shinyoung Park, Joon Soo Kim, Young Tag Ko, Dong-Kug Choi
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
lipopolysaccharide
solid lipid nanoparticle
curcumin
antineuroinflammation
toxicity
SEM
Online Access:https://www.mdpi.com/1420-3049/24/6/1170

Internet

https://www.mdpi.com/1420-3049/24/6/1170

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