Comparative Genome-Scale Metabolic Modeling of Metallo-Beta-Lactamase–Producing Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates

Comparative Genome-Scale Metabolic Modeling of Metallo-Beta-Lactamase–Producing Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates

The emergence and spread of metallo-beta-lactamase–producing multidrug-resistant (MDR) Klebsiella pneumoniae is a serious public health threat, which is further complicated by the increased prevalence of colistin resistance. The link between antimicrobial resistance acquired by strains of Klebsiella...

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Bibliographic Details
Main Authors: Charles J. Norsigian, Heba Attia, Richard Szubin, Aymen S. Yassin, Bernhard Ø. Palsson, Ramy K. Aziz, Jonathan M. Monk
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
multi-drug resistance
MDR
Klebsiella pneumoniae
colistin
genome-scale modeling
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00161/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00161/full

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