Development of a Hierarchical Support Vector Regression-Based In Silico Model for Caco-2 Permeability

Drug absorption is one of the critical factors that should be taken into account in the process of drug discovery and development. The human colon carcinoma cell layer (Caco-2) model has been frequently used as a surrogate to preliminarily investigate the intestinal absorption. In this study, a quan...

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Bibliographic Details
Main Authors: Giang Huong Ta, Cin-Syong Jhang, Ching-Feng Weng, Max K. Leong
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/13/2/174