Development of a Hierarchical Support Vector Regression-Based In Silico Model for Caco-2 Permeability
Drug absorption is one of the critical factors that should be taken into account in the process of drug discovery and development. The human colon carcinoma cell layer (Caco-2) model has been frequently used as a surrogate to preliminarily investigate the intestinal absorption. In this study, a quan...
Main Authors: | Giang Huong Ta, Cin-Syong Jhang, Ching-Feng Weng, Max K. Leong |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/13/2/174 |
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