Increased CD39 nucleotidase activity on microparticles from patients with idiopathic pulmonary arterial hypertension.

BACKGROUND:Idiopathic pulmonary arterial hypertension (IPAH) is a devastating disease characterized by increased pulmonary vascular resistance, smooth muscle and endothelial cell proliferation, perivascular inflammatory infiltrates, and in situ thrombosis. Circulating intravascular ATP, ADP, AMP and...

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Bibliographic Details
Main Authors: Scott H Visovatti, Matthew C Hyman, Diane Bouis, Richard Neubig, Vallerie V McLaughlin, David J Pinsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3394716?pdf=render