Increased CD39 nucleotidase activity on microparticles from patients with idiopathic pulmonary arterial hypertension.
BACKGROUND:Idiopathic pulmonary arterial hypertension (IPAH) is a devastating disease characterized by increased pulmonary vascular resistance, smooth muscle and endothelial cell proliferation, perivascular inflammatory infiltrates, and in situ thrombosis. Circulating intravascular ATP, ADP, AMP and...
Main Authors: | Scott H Visovatti, Matthew C Hyman, Diane Bouis, Richard Neubig, Vallerie V McLaughlin, David J Pinsky |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3394716?pdf=render |
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