An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the <it>HLA-DRB1 </it>gene

An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the <it>HLA-DRB1 </it>gene

<p>Abstract</p> <p>Background</p> <p>Multiple sclerosis (MS) is a complex trait in which genes in the MHC class II region exert the single strongest effect on genetic susceptibility. The principal MHC class II haplotype that increases MS risk in individuals of Northern...

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Bibliographic Details
Main Authors: Sadovnick A Dessa, Dyment David A, McMahon Roisin, Ramagopalan Sreeram V, Ebers George C, Wittkowski Knut M
Format: Article
Language:English
Published: BMC 2009-02-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/10/10

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http://www.biomedcentral.com/1471-2350/10/10

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