Elucidating nanoscale mechanical properties of diabetic human adipose tissue using atomic force microscopy

Abstract Obesity-related type 2 diabetes (DM) is a major public health concern. Adipose tissue metabolic dysfunction, including fibrosis, plays a central role in DM pathogenesis. Obesity is associated with changes in adipose tissue extracellular matrix (ECM), but the impact of these changes on adipo...

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Bibliographic Details
Main Authors: J. K. Wenderott, Carmen G. Flesher, Nicki A. Baker, Christopher K. Neeley, Oliver A. Varban, Carey N. Lumeng, Lutfiyya N. Muhammad, Chen Yeh, Peter F. Green, Robert W. O’Rourke
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77498-w